Viscoelastic deformation of lipid bilayer vesicles

Deformation of giant lipid bilayer vesicles in shear flow

We describe experimental studies of the deformation of giant lipid bilayer vesicles in shear flow. The experiments are carried out with a counterrotating Couette apparatus. The deformation depends on the mechanical properties of the lipid bilayer, the vesicle radius, and the viscosity of the surrounding Newtonian liquid. We show that the relevant mechanical parameter is the bending rigidity. A ...

Rheological Behavior of a Dispersion of Small Lipid Bilayer Vesicles

Rheological behavior of a dispersion of small nearly-unilamellar phospholipid bilayer vesicles has been investigated. We conducted steady-state shear experiments and linear viscoelastic experiments. In the dilute and semidilute regime the rheological behavior is similar to that of a hard-sphere dispersion as reported in the literature for viscoelasticmeasurements, butnowalso observed in steady ...

Formation and properties of cell-size lipid bilayer vesicles.

Hydration of single or mixed phospholipids or lipid protein mixtures at low ionic strength results in the formation of a population of large, solvent free, single bilayer vesicles with included volumes of up to 300 microliters/mumol lipid. Their size ranges from 0.1 to 300 microns and they can be sorted out according to size by centrifugation. When formed in distilled water their internal solut...

3. Bilayer Adaptability and Elasticity of Mixed Lipid Vesicles, Transfersome

Vesicles surfing on a lipid bilayer: self-induced haptotactic motion.

Haptotaxis is a mechanism proposed at the end of the 1960s to explain cell motility. It describes cell movement induced by an adhesion gradient. In this work, we present evidence for self-induced haptotaxis using negatively charged giant vesicles interacting with positively charged supported lipid bilayers, which has not been previously described. Depending on the charge of the vesicle, we obse...